Mario I ROMERO-ORTEGA,Sanjay ANAND,Nesreen ALSMADI,Geetanjali S BENDALE
申请号：
US16755089
公开号：
US20200237867A1
申请日:
2018.10.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
In one aspect, methods of promoting asymmetric nerve growth and/or regeneration are described herein. In some embodiments, such a method comprises exposing a population of transected or severed nerves to a first molecular growth cue and to a second molecular growth cue. The population of transected nerves comprises one or more nerves of a first nerve type and one or more nerves of a second nerve type differing from the first nerve type. Additionally, the first molecular growth cue preferentially promotes growth of the first nerve type, as compared to the second nerve type. Similarly, the second molecular growth cue preferentially promotes growth of the second nerve type, as compared to the first nerve type. Moreover, the first molecular growth cue is spatially separated from the second molecular growth cue.
