Refers to a Crystalline form of Hemi hydrate is (S) - N - (S) - 1 - (Cyclohexyl - {2 - (S) - 2 - [4 - (4 - fluoro benzoyl) - thiazol-2-yl] - pyrrolidin-1-yl} - 2 - oxo - ethyl) - 2 - methyl - amino propionamide of formula (i) comprising a Powder diffraction pattern of x-ray which includes 2 Theta values such as 8.3 9.5 17.3 13.5 and 18.2 18.5 (0.2 at room temperature.It also relates to a Pharmaceutical composition. The Crystalline form is an inhibitor of Apoptosis Proteins (IAPs), being useful in the treatment of cancerSe refiere a una forma cristalina del hemi-hidrato HA de (S)-N-((S)-1-ciclohexil-2-{(S)-2-[4-(4-fluoro-benzoil)-tiazol-2-il]-pirrolidin-1-il}-2-oxo-etil)-2-metil-amino-propionamida de formula (I) que comprende un patron de difraccion en polvo de rayos-X que comprende valores 2 theta tales como 8,3 9,5 13,5 17,3 18,5 y 18,2 ± 0.2 a temperatura ambiente. Tambien se refiere a una composicion farmaceutica. Dicha forma cristalina es un inhibidor de las proteinas de apoptosis (IAPs), siendo util en el tratamiento del cancer
