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POLYMER COMPOSED OF REPEAT UNITS HAVING A BIOLOGICALLY ACTIVE MOLECULE ATTACHED THERETO VIA A PH-SENSITIVE BOND
专利权人:
SPIREA LIMITED
发明人:
Myriam Marie Ouberai,Mark Welland
申请号:
US16892569
公开号:
US20200289531A1
申请日:
2020.06.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
There is provided a polymer comprising: (i) a repeat unit derived from a compound of formula (I) (Formula (I)) wherein, R1 and R2 are each independently selected from OH, OR′;, SH, SR′;, NH2, NHR′; and NR′;2; R′; is C1-20 hydrocarbyl; each n is independently 0 or an integer between 1 and 6; each m is independently 0 or an integer between 1 and 4, and preferably at least one m is 1; and q is an integer between 1 and 8; and; (ii) a biologically active molecule, wherein said biologically active molecule is covalently bonded to said repeat unit; as well as methods for preparing such polymers, particles comprising said polymers and uses of said polymers and particles including use in the treatment of disease.
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