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5-[(PIPERAZIN-1-YL)-3-OXO-PROPYL]-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AS ADAMTS INHIBITORS FOR TREATING OSTEOARTHRITIS
专利权人:
发明人:
申请号:
RU2017126187
公开号:
RU2017126187A3
申请日:
申请国别(地区):
RU
年份:
2019
代理人:
摘要:
The present invention discloses compounds according to formula I:Wherein R<;sup>;1<;/sup>;, R<;sup>;2<;/sup>;, R<;sup>;3a<;/sup>;, R<;sup>;3b<;/sup>;, and Cy are as defined herein.The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and the compounds of formula I for use in methods of treatment and for use in methods of prophylaxis and/or treatment of inflammatory conditions, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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