A urea derivative or a Salt of this acceptable from the point of view that have a pharmacological effect of a receptor agonist Peptide Type 1 Formilo (abbreviated as fprl1), a Pharmaceutical composition containing the derivative or the Salt of this acceptable urea from the pun To pharmacologically.Useful for the treatment, prevention or suppression of inflammatory diseases, Chronic Respiratory Diseases, cancers, septicemia, Allergic Symptoms, retrovirus, HIV infection, Circulatory disorders, neuroinflammation, Nervous disorders, pain Prion u00f3sicas, diseases, amyloidosis, immune disorders, and the like.Claim 1, characterized in that: a compound represented by the General formula (1) or a Salt of this pharmacological acceptable from the point of View: where, in the formula (1), ar u00b9 is a phenyl Group substituents which has Optionally, a group heterociclilo Aromatic mono Which has optionally cyclic SubstituentOr a group heterociclilo Aromatic bicyclic has 9 or 10 Atoms and optionally substituents； ar u00b2 is a phenyl Group substituents which has optionally (always when is the rest of Formula A1, the phenyl Group substituents are only Halogen Atoms whose ex Including), a group which has optionally heterociclilo monocyclic Aromatic substituents.Or a group heterociclilo Aromatic bicyclic has 9 or 10 Atoms and optionally substituents； is a group selected from the group consisting of A1, A2, A3, A4 and A5) in the group of formulas (2)； where r u00b9 and R u00b2 are independently a hydrogen Atom or a Group c u2081 u208b u2086 is optionally alkyl substituents.Or r u00b9 and R u00b2 together form a Group c u2082 u208b u2086 alquileno； r u00b3 is a hydrogen Atom or a Group c u2081 u208b u2086 is optionally alkyl substituents； X is an oxygen Atom and a Sulfur Atom or SO u2082； b is a group that has heterociclilo optionally substituents； and each C Atom Arbon marked with an Asterisk is an Asymmetric carbon Atom.Un derivado de urea o una sal de este aceptable desde el pun
