SLOW-RELEASE CONJUGATES OF SN-38
- 专利权人:
- PROLYNX LLC
- 发明人:
- Gary W. ASHLEY,Eric L. SCHNEIDER
- 申请号：
- US15026579
- 公开号：
- US20160243106A1
- 申请日:
- 2014.10.03
- 申请国别(地区):
- US
- 年份:
- 2016
- 代理人:
- 摘要：
- Conjugates of SN-38 that provide optimal drug release rates and minimize the formation of the corresponding glucuronate are described. The conjugates release SN-38 from a polyethylene glycol through a β-elimination mechanism.
- 来源网站：
- 中国工程科技知识中心
