Slow-release conjugates of SN-38
- 专利权人:
- ProLynx LLC
- 发明人:
- Gary W. Ashley,Eric L. Schneider
- 申请号:
- US16009078
- 公开号:
- US10342792B2
- 申请日:
- 2018.06.14
- 申请国别(地区):
- US
- 年份:
- 2019
- 代理人:
- 摘要:
- Conjugates of SN-38 that provide optimal drug release rates and minimize the formation of the corresponding glucuronate are described. The conjugates release SN-38 from a polyethylene glycol through a β-elimination mechanism.
- 来源网站:
- 中国工程科技知识中心