Anne Marie Foley;Karen Viviane Lucile Crépy;Helen Tracey Horsley;Bénédicte Irma Léonce Frédé;William Mark Jones;Pavandeep Singh Aujla;Rikki Peter Alexander;Richard Jeremy Franklin;Alan Findlay Haughan
发明人:
Rikki Peter Alexander,Pavandeep Singh Aujla,Karen Viviane Lucile Crépy,Anne Marie Foley,Richard Jeremy Franklin,Alan Findlay Haughan,Helen Tracey Horsley,William Mark Jones,Bénédicte Irma Léonce Frédé
申请号:
US12306151
公开号:
US08242116B2
申请日:
2007.06.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A series of 6,7-dihydro[1,3]thiazolo[5,4-c]pyridin-4(5H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.