DELLINGER, DOUGLAS J.,SIERZCHALA, AGNIESKA,TURNER, JOHN,MYERSON, JOEL,KUPIHAR, ZOLTAN,FERREIRA, FERNANDO,CARUTHERS, MARVIN H.
申请号:
PL12163999
公开号:
PL2476689T3
申请日:
2008.05.09
申请国别(地区):
PL
年份:
2016
代理人:
摘要:
Aspects of the invention include 2'-protected nucleoside monomers that are protected at the 2'-site with thiocarbon protecting groups. Thiocarbon protecting groups of interest include thiocarbonate, thionocarbonate, dithiocarbonate groups, as well as thionocarbamate protecting groups. Aspects of the invention further include nucleic acids that include the protecting groups of the invention, as well as methods of synthesizing nucleic acids using the protecting groups of the invention.