DERIVE DE (AZA)INDOLE SUBSTITUE EN POSITION 5, COMPOSITION PHARMACEUTIQUE LE COMPRENANT, COMPOSES INTERMEDIAIRES ET LEUR PROCEDE DE PREPARATION

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专利权人:

AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.

发明人:

ALISI, MARIA ALESSANDRA,FURLOTTI, GUIDO,CAZZOLLA, NICOLA,MAUGERI, CATERINA,DRAGONE, PATRIZIA,GAROFALO, BARBARA,COLETTA, ISABELLA,MANGANO, GIORGINA,GARRONE, BEATRICE

申请号：

CA2707339

公开号：

CA2707339C

申请日:

2008.12.16

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

An (aza)indole derivative substituted in position 5, of formula (I) in whichX, Y,Z, G1, G2, G3, R1. W and R2 have the meanings given in the description, apharmaceutical composition comprising it, and also intermediate compounds andapreparation process therefor. There is provided in a preferred embodiment useof thederivative for inhibiting mPGES-1 and/or anti-nociceptive activity ininflammatory pain.(see formula I)

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