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MONOKLONSKA PROTUTIJELA
专利权人:
The Regents of the University of California
发明人:
Akassoglou, Katerina
申请号:
HRP20170110
公开号:
HRP20170110T1
申请日:
2017.01.23
申请国别(地区):
HR
年份:
2017
代理人:
摘要:
The present invention provides an isolated antibody that binds a fibrin or fibrinogen γC domain. In various aspects, the antibody inhibits microglial adhesion to the fibrin or fibrinogen γC domain, inhibits Mac-1 binding to the fibrin or fibrinogen γC domain, and/or suppresses clinical symptoms of Experimental Autoimmune Encephalomyelitis (EAE). Various methods of using the antibodies, pharmaceutical compositions, kits, vectors, cells comprising the vectors, and antibody generating methods are provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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