THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
GERARD KARSENTY,PATRICIA F. DUCY,YULI XIE,DONALD LANDRY,VIJAY YADAV
申请号：
BRPI0908719
公开号：
BRPI0908719A2
申请日:
2009.03.30
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis and the agents are TPH1 inhibitors or serotonin receptor antagonists.
