The present invention relates to a compound of the general formula (II) or a salt or solvate thereof, as well as medical uses involving them, wherein A1 is selected from the group consisting of N and C-R8； A2 is selected from the group consisting of N and C-R3, A3 is selected from the group consisting of N and C-R9； A4 and A5 and A6 are independently selected from the group consisting of N and C-R1； R1 is selected from the group consisting of hydrogen, (C1-C3)alkyl, halogen, (C1-C3)alkoxy, and (C1-C3)haloalkyl； R2 is selected from the group consisting of hydrogen, halogen, and (C1-C3)alkyl； R3 is selected from the group consisting of hydrogen, (C1-C3)alkyl, NR4R5, (C1-C3)alkyl- NR4R5, and cyano, wherein R4 and R5 are independently selected from the group consisting of hydrogen, (C3-C5)cycloalkyl, (C3-C5)heterocycloalkyl and (C1-C3)alkyl, or R4 and R5 together with the nitrogen atom to which they are attached form a 5- to 7-membered heterocyclic ring optionally comprising in addition to the aforementioned nitrogen atom a further heteroatom group selected from the group consisting of O and NR6, wherein R6 is selected from the group consisting of hydrogen, methyl, acetyl and formyl； Y is selected from the group consisting of O and S； R8 is selected from the group consisting of (C1-C4)alkyl, (C3-C5)cycloalkyl and (C3-C5)heterocycloalkyl； and R9 is selected from the group consisting of hydrogen, (C1-C3)alkyl and (C1-C3)alkoxy； wherein certain particular compounds are excluded py proviso, and methods for producing such compounds.
