Masaharu Nakamura,Masayuki Kitagawa,Keiichirou Yamamoto,Chieko Seno
申请号:
US15159947
公开号:
US20160279164A1
申请日:
2016.05.20
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Provided is a high-molecular weight conjugate of resorcinol derivatives which is excellent in water solubility and stability and has high antitumor activity even when used in a smaller total drug amount than the resorcinol derivatives. The high-molecular weight conjugate of resorcinol derivatives comprises a structure in which a carboxyl group of polymer moiety having a carboxyl group in the side chain and polyethylene glycol moiety is linked to a hydroxyl group of resorcinol derivatives via an ester bond.