COMBINATIONS OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVATORS AND mGluR5 ANTAGONISTS FOR USE IN DOPAMINE INDUCED DYSKINESIA IN PARKINSONS DISEASE
Therese Di Paolo,Baltazar Gomez-Mancilla,Cristina Lopez-Lopez,Donal Johns
申请号：
US14005892
公开号：
US20140228398A1
申请日:
2012.03.16
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to novel combinations suitable for the treatment of dyskinesia associated with dopamine agonist therapy in Parkinsons Disease, which comprise, as active ingredients, at least one low molecular weight nicotinic acetylcholine receptor alpha 7 activator and at least one low molecular weight metabotropic glutamate receptor 5 antagonist to their preparation to their use as medicaments and to medicaments comprising them.
