Disclosed is an adhesive patch composed of an adhesive base agent and a supporting body wherein the adhesive base agent contains 3-30% by mass of a low-molecular-weight polyisobutylene and aluminum hydroxide and/or titanium oxide but not substantially containing water. Also disclosed is a skin irritation reducing agent used therefore. Further disclosed is an adhesive patch composed of a supporting body and an adhesive base agent which contains a thermoplastic rubber and a low-moleculer-weight polyisobutylene but not substantially containing water. This adhesive patch is characterized in that the adhesive base agent further contains aluminum hydroxide and/or titanium oxide. Also disclosed is a skin irritation reducing agent used for such an adhesive patch.