Use of pantothenol or its ester and/or pantothenic acid or its salts together and/or in combination with imidazoline-based alpha-sympathomimetic activity or its salts, used to treat rhinitis and/or to prepare drug for treating rhinitis
Maria Clementine Martin Klosterfrau Vertriebsgesellschaft mbH
发明人:
GREVE, HARALD,Harald Greve
申请号：
DE102012011447
公开号：
DE102012011447A1
申请日:
2012.05.15
申请国别(地区):
DE
年份:
2013
代理人:
摘要：
Die Erfindung betrifft die Verwendung von Pantothenol (Dexpanthenol) oder dessen physiologisch unbedenklichen Ester bzw. von Pantothensäure oder deren physiologisch unbedenklichen Salzen zur Verringerung der unerwünschten systemischen Resorption von imidazolinbasierten alpha-Sympathomimetika bei deren topischen, insbesondere nasalen, bevorzugt intranasalen Applikation im Rahmen der Behandlung von Rhinitis.Use of (a) pantothenol (dexpanthenol) or its ester and/or pantothenic acid or its salt together and/or in combination with (b) at least one imidazoline-based alpha -sympathomimetic activity or its salts for the reduction of the systemic resorption of the imidazoline-based alpha -sympathomimetic activity with the treatment of rhinitis and/or for preparing a drug for treating rhinitis, is claimed. An independent claim is included for a combination therapeutic agent in form of a pharmaceutical composition for the treatment of rhinitis for reducing imidazoline-based alpha -sympathomimetic activity, where the pharmaceutical composition contains (a) and (b). ACTIVITY : Antiallergic； Antiinflammatory. MECHANISM OF ACTION : None given.
