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SPIROCYCLIC AMILORIDE ANALOGUES AS ENAC BLOCKERS
专利权人:
NOVARTIS AG
发明人:
GURDIP BHALAY,STEPHEN PAUL COLLINGWOOD,EMMA BUDD,PAUL OAKLEY,NICHOLA SMITH,GRAHAM CHARLES BLOOMFIELD,PETER HUNT,ANDREW DUNSTAN,LEE EDWARDS,PETER GEDECK,CATHERINE HOWSHAM,THOMAS ANTHONY HUNT
申请号:
PT11184004
公开号:
PT2444120T
申请日:
2008.12.09
申请国别(地区):
PT
年份:
2018
代理人:
摘要:
A compound of Formula I in free or salt or solvate form, where R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and R 11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
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