PURPOSE: A pharmaceutical composition and a health functional food containing a purple-fleshed sweet potato extract are provided to lower subcutaneous fat amount and triglyceride and cholesterol content and to prevent and treat obesity, hypercholesterolemia, and hyperlipidemia. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity, hyperlipidemia, hypercholesterolemia, or hypertriglyceridemia contains a purple-fleshed sweet potato extract as an active ingredient. The extract is prepared using hot water or low carbon number alcohol of C2-C4. The hot water extraction is performed at 80-105 deg.C. for 0.5-24 hours. A health functional food for treating obesity, hyperlipidemia, hypercholesterolemia, or hypertriglyceridemia due to fat accumulation contains the extract as an active ingredient. [Reference numerals] (AA) Control group； (BB) Embodiment 1； (CC) Embodiment 2 EtOH fractionation； (DD) Embodiment 2 EtOAc fractionation； (EE) Embodiment 2 EtOH fractionation + EtOAc fractionation 본 발명은 자색고구마 추출물을 유효성분으로 하는 의약 조성물 및 건강기능식품에 관한 것으로, 아지방세포의 지방세포로의 전환과 지방축적을 강하게 억제함은 물론, 고지방식이에 의한 체중 증가를 억제하고, 피하지방의 양을 감소시키며, 혈중 렙틴 농도, 트리글리세라이드 및 콜레스테롤 함량을 낮추어, 비만, 고지질혈증, 고콜레스테롤혈증, 고트리글리세라이드혈증 등의 치료 및 예방용 의약 조성물 및 건강기능식품으로 활용될 수 있다.
