The present invention relates to a device, system and method for evaluating the microcirculation of blood in a tissue, the device being characterised in that it includes: a housing (8) comprising an open end (82) intended to be placed in contact with said tissue and to thus delimit an area of study of said tissue; means (2) for emitting light toward the area of study; means (1) for acquiring images of the area of study; means (3, 6) for compressing at least one defined zone (10) inside the area of study, said compressing means (3, 6) being calibrated to apply a controlled pressure to said zone (10) and retractable in order to leave said area of study accessible to said light and to the image-acquiring means (1); controlling means (80, 9) controlling application of said controlled pressure to said zone (10) in a first defined period of time, then the removal of said controlled pressure and the acquisition of images of said area of study exposed to said light in a second defined period of time; and data-processing means (800, 90) using the acquired images to calculate at least one parameter relating to the decoloration and/or recoloration of said tissue.La présente invention concerne un dispositif, un système et un procédé d'évaluation de la microcirculation sanguine d'un tissu, le dispositif étant caractérisé en ce qu'il comporte un boîtier (8) comprenant une extrémité (82) ouverte, destinée à être placée au contact dudit tissu et délimiter ainsi une surface d'étude dudit tissu, des moyens d'émission de lumière (2) vers la surface d'étude, des moyens d'acquisition d'images (1) de la surface d'étude, des moyens de compression (3, 6) d'au moins une zone déterminée (10) à l'intérieur de la surface d'étude, lesdits moyens de compression (3, 6) étant calibrés pour appliquer une pression contrôlée sur ladite zone (10) et rétractables pour laisser ladite surface d'étude accessible à ladite lumière et aux moyens d'acquisition d'images (1), des moyens de contrôle (80, 9) cont