GENETICALLY ENCODED FLUORESCENT SENSORS FOR DETECTING LIGAND BIAS AND INTRACELLULAR SIGNALING THROUGH cAMP PATHWAYS

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专利权人:

Montana Molecular LLC

发明人:

HUGHES, Thomas, E.,TEWSON, Paul, H.,QUINN, Anne, Marie

申请号：

EP14858784

公开号：

EP3065754A4

申请日:

2014.11.04

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Described herein are novel fluorescent sensors for cyclic adenosine monophosphate (cAMP) that are based on single fluorescent proteins. These sensors use less visible spectrum than FRET-based sensors, produce robust changes in fluorescence, and can be combined with one another, or with other sensors, in a multiplex assay on standard fluorescent plate readers or live cell imaging systems.

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中国工程科技知识中心

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http://www.ckcest.cn/home/