The Broad Institute, Inc.;Dana-Farber Cancer Institute, Inc.;The General Hospital Corporation d/b/a Massachusetts General Hospital
发明人:
Florence Fevrier Wagner,Jennifer Q. Pan,Sivaraman Dandapani,Andrew Germain,Edward Holson,Benito Munoz,Partha P. Nag,Michael C. Lewis,Stephen J. Haggarty,Joshua A. Bishop,Kimberly Stegmaier,Michel Weiw
申请号：
US14799281
公开号：
US20150313890A1
申请日:
2015.07.14
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3α or GSK3β) or CK1) activity. The present invention further provides methods of using the compounds described herein for treating kinase-mediated disorders, such as neurological diseases, psychiatric disorders, metabolic disorders, and cancer.
