Biological materials and uses thereof

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专利权人:

BioInvent International AB

发明人:

Frendeus, Bjorn,Carlsson, Roland

申请号：

AU2012216655

公开号：

AU2012216655A1

申请日:

2012.09.05

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

#$%^&*AU2012216655A120120927.pdf#####ABSTRACT The invention provides binding molecules, including antibody molecules which selectively bind to a cell surface antigen of a target cell, and wherein the binding molecules, on binding the cell surface antigen, induce apoptosis of the target cell. There is also provided methods of and pharmaceutical compositions for apoptosis induction and uses thereof.2/19 scFv F1 scFv B1 1Goo 7o 4000 6 0 00 GooSo 1000 0 200 400 900 800 1000 FSC44:: FSC*sght FSC-H. PSC-ieigt scFv F1 scFvBl1 1000 1ION B. 0 1 10. 1 10 100 10o0w 10 100 1000 FL14H= Annexin FL 4t=Anneil Figure 2

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