The invention concerns a system and a method of use of said system forperforming fluid administration on a patient, the system comprising: -a liquidpump (1), - a liquid distribution system (2) connected to said pump (1) insuch a way that liquid can flow from the liquid distribution system (2) to thepump (1) and vice versa, - liquid supply means (3) for supplying liquid to apatient (4) via said liquid distribution system (2) and said pump (1), - apatient conduit (5) adapted for connecting said liquid distribution system (2)to a patient (4), the system being characterized by the fact that said liquiddistribution system (2) comprises two distinct hub chambers (7,8), the firsthub chamber (7) including at least one liquid supply port with dedicated valvemeans (9), one patient port with dedicated valve means (10) and one pump inlet(26), the second hub chamber (8) including at least, one patient port (18) orwarmer port (16) with dedicated valve means and one pump outlet (27), saidsystem furthermore comprising control means arranged to close said patientport (10) of the first hub chamber (7) when said liquid supply port (9) isopen and vice versa.