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1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4h-pyrrolo[3,2-d]pyrimidin-4-ones as inhibitors of myeloperoxidase
专利权人:
ASTRAZENECA AB
发明人:
申请号:
IL25243617
公开号:
IL252436D0
申请日:
2017.05.22
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
There are disclosed certain 1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-one compounds of formula (I), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme MPO and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disorders such as heart failure and coronary artery disease related conditions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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