THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;INOVIO PHARMACEUTICALS, INC.
发明人:
WEINER, David,MORROW, Matthew,WISE, Megan
申请号：
USUS2016/023126
公开号：
WO2016/153995A1
申请日:
2016.03.18
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Disclosed is a vaccine comprising an antigen and CD40L, wherein the antigen may be encoded by a first nucleic acid and CD40L may be encoded by a second nucleic acid. Also disclosed are methods for increasing an immune response in a subject, the methods comprise administering the vaccine to the subject in need thereof. Further disclosed is the antigen selected from the group consisting of a human papilloma virus (HPV) antigen, a human immunodeficiency virus (HIV) antigen, an influenza antigen, and a Plasmodium falciparum antigen.L'invention concerne un vaccin comprenant un antigène et CD40L. L'invention concerne également des méthodes permettant d'augmenter la réponse immunitaire chez un sujet. Les méthodes consistent à administrer le vaccin au sujet nécessitant un tel traitement.
