NOUVEAUX SELS DE 3-[(DIMETHYLAMINO)METHYL]-N-{2-[4-(HYDROXYCARBAMOYL)PHENOXY]ETHYL}-1-BENZOFURANE-2-CARBOXAMIDE, FORMES CRISTALLINES APPARENTEES, PROCEDE POUR LEUR PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT

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专利权人:

PHARMACYCLICS LLC

发明人:

GAILLARD, MARINA,LETELLIER, PHILIPPE

申请号：

CA2960044

公开号：

CA2960044A1

申请日:

2015.09.03

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Described herein are salts of 3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl)phenoxyl]ethyl} -1-benzofuran-2-carboxamide, in particular that of formula (I): (Formula (I)) wherein HA is naphthalene-1,5-disulfonic acid, naphthalene-2-sulfonic acid, oxalic acid, benzenesulfonic acid, or sulfuric acid, or hydrates thereof and crystalline forms thereof characterized by the powder X-ray diffraction diagram and the 13C CP/MAS NMR solid state spectrum. Also described are compositions, methods of use or preparation thereof.

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