A medicine packaging apparatus has a medicine supply means (1) for supplying a medicine according to a prescription data a medicine standby means (11) for temporarily holding the medicine supplied by the medicine supply means and having the medicine stand by a printing means (2) for printing a relevant data on a packaging paper according to the prescription data a packaging paper conveyance means for conveying the packaging paper (15) and a medicine packaging means (3) for packaging the medicine supplied by the medicine supply means into the packaging paper in a packaging position. The apparatus includes a medicine detecting means (8d, 13a/b/c) for detecting medicine supplied to the standby means. The apparatus is controlled for allowing the packaging paper conveyance means to convey a portion of the packaging paper, on which the relevant data is printed by the printing means, to the packaging position and allowing the medicine packaging means to package the corresponding medicine standing by in the medicine standby means.