A pharmaceutical composition for inhibiting precursor osteoclast growth is disclosed in the present invention. The pharmaceutical composition includes a compound represented by a formula (I), and a pharmaceutically acceptable salt and excipient:wherein R1、R2、R3、R4can be one selected from a group consisting of hydrogen, halogen, C1~C10alkyl group, C2~C10alkynyl group, amino group, haloalkyl group and sulfonamide group.本發明提供一種用以抑制前驅蝕骨細胞生長的醫藥組合物,包含如式I所示之化合物及其藥學上可接受之鹽與賦形劑:式I中,R1、R2、R3、R4可選擇自由氫元素、鹵素、C1-10烷基、鹵烷基、胺基、C2-10炔基或磺醯胺基所組成之群組。