Musc Foundation for Research Development;Department of Veterans Affairs
发明人:
TOMLINSON, Stephen,ADKINS, DeAnna,ALAWIEH, Ali
申请号:
EP17861529
公开号:
EP3526248A4
申请日:
2017.10.17
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention describes compositions and method for improving outcomes after injury to the central nervous system wherein complement signaling is activated. In one aspect, the method comprises administering to a subject a therapeutically effective amount of a therapeutic agent comprising a targeted inhibitor molecule comprising a targeting portion and an inhibitor portion, wherein the molecule inhibits complement, and wherein therapeutic agent is administered in combination with rehabilitation therapy or thrombolytic agent.