The present invention relates to salts and crystalline forms of 2-(3-(8-Amino-6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3-yl)-4-methylphenyl)-3,3,3-trifluoro-2-hydroxypropanamide, crystalline forms of 8-amino-N-(2-hydroxy-2-methylpropyl)-3-(2-methyl-5-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide, and crystalline forms of 8-amino-N-(2-hydroxy-2-methylpropyl)-3-(2-(methyl-d3)-5-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide, which are PI3K inhibitors useful in the treatment of cancer and other diseases.本發明係關於2-(3-(8-胺基-6-(三氟甲基)咪唑并[1,2-a]吡嗪-3-基)-4-甲基苯基)-3,3,3-三氟-2-羥基丙醯胺之鹽及結晶形式、8-胺基-N-(2-羥基-2-甲基丙基)-3-(2-甲基-5-(1,1,1-三氟-2-羥基丙-2-基)苯基)咪唑并[1,2-a]吡嗪-6-甲醯胺之結晶形式及8-胺基-N-(2-羥基-2-甲基丙基)-3-(2-(甲基-d3)-5-(1,1,1-三氟-2-羥基丙-2-基)苯基)咪唑并[1,2-a]吡嗪-6-甲醯胺之結晶形式，其為適用於治療癌症及其他疾病之PI3K抑制劑。
