A surgical radiological C-arm imaging unit drape configured to provide a sterile outer surface about an end portion of a C-arm imaging unit and method of providing a sterile surface about an end of a C-arm imaging unit is provided. The drape includes a flexible enclosure having an upper wall with a pair of sidewalls and a rear side extending downwardly from the upper wall. The upper wall and the side walls are extendible between expanded and collapsed positions. When in the expanded position, a pocket sized for receipt of the end portion of the imaging unit beneath the upper wall is formed. The upper wall has a sterile outer surface configured to face away from and overlie the end portion of the imaging unit to maintain sterility in a sterile zone above an operating table. When in the collapsed position, the sterile outer surface shielded from external contamination.