MILEK FRANK DR.,ROUVEN JOSL DR.,Milek Frank Dr.,Rouven Josl Dr.
申请号：
SI201030213
公开号：
SI2433651T1
申请日:
2010.09.03
申请国别(地区):
SI
年份:
2013
代理人:
摘要：
Quantitatively determining impurities in the form of aldehydes and ketones in glycerol processing for the production of drugs, comprises reacting the glycerol containing the impurities in a sample solution with a derivatizing reagent and determining the amount of derivatized impurities, where the derivatizing reagent is O-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine hydrochloride； the derivatization is carried out in the presence of a solubilizer in the form of a polar organic solvent； and a separation by liquid chromatography and a detection of the separated impurities are carried out.
