Methods, devices, systems, and kits useful for the collection and analysis of samples obtained by swabs are disclosed. Swab containers configured for receiving a swab containing a sample； cartridges for holding one or more of: a swab container, a swab, assay units, pipette tips, vessels, transport units, and implements； systems (which may include a sample processing device)； kits； and methods for their use are disclosed. A swab container may include an entry port； an assay chamber having an assay port； a conduit comprising an interior channel connecting the entry port； and an interior channel providing fluidic communication between the entry port and assay chamber. An interior channel may be configured to squeeze a portion of a swab placed in or through the conduit. A cartridge may include a cartridge frame configured to receive one or more of swab containers, assay units, transport units, pipette tips, vessels or implements.
