A nasal sprayer having a formulation comprising olopatadine is provided.A spray of the formulation is delivered to a subject's nose. The spray mayhave aspray characteristic comprising a spray pattern having a longest axis of 20-45mm,a shortest axis of 14-20 mm, and an ellipticity of 1-1.8. The spray may alsohave aspray characteristic comprising a droplet size distribution having a D10 of 15-30 µm,a D50 of 30-60 µm, a D90 of 50-150 µm, a SPAN of not more than 3, and a% Volumeof <； 10 µm of less than 4%.
