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METHOD OF DELIVERING NASAL SPRAY
专利权人:
Novartis AG
发明人:
Gerald D. Cagle,G. Michael Wall
申请号:
US14079730
公开号:
US20140227326A1
申请日:
2013.11.14
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method of delivering a nasal spray. A sprayer having a formulation comprising olopatadine is provided. A spray of the formulation is delivered to a subject's nose. The spray may have a spray characteristic comprising a spray pattern having a longest axis of 20-45 mm, a shortest axis of 14-20 mm, and an ellipticity of 1-1.8. The spray may also have a spray characteristic comprising a droplet size distribution having a D10 of 15-30 μm, a D50 of 30-60 μm, a D90 of 50-150 μm, a SPAN of not more than 3, and a % Volume of <;10 μm of less than 4%.
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