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Method for detecting an FGFR3/TACC3 fusion protein, or encoding gene thereof
专利权人:
JAPANESE FOUNDATION FOR CANCER RESEARCH
发明人:
Kengo Takeuchi
申请号:
US15113599
公开号:
US10048277B2
申请日:
2015.01.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A polynucleotide, which is a novel causative gene for cancer, is elucidated, and, based on this finding, provided are a method for detecting the polynucleotide, or a polypeptide encoded by the polynucleotide; a kit and a primer set for the detection; a method for screening an inhibitor of the polypeptide; and a pharmaceutical composition for treating a cancer containing the inhibitor. In the detection method of the present invention, an FGFR3 fusion protein, or a fusion gene encoding the fusion protein, or a TACC3 fusion protein, or a fusion gene encoding the fusion protein, is detected in a sample derived from female genitalia obtained from a subject.
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