PROCÉDÉS ET COMPOSITIONS COMPRENANT DES LIPIDES CATIONIQUES POUR STIMULER DES GÈNES D'INTERFÉRON DE TYPE 1

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专利权人:

PDS Biotechnology Corporation

发明人:

申请号：

EP18886648.7

公开号：

EP3720423A1

申请日:

2018.12.05

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Methods and compositions for modifying type I IFN signaling pathways in a subject comprising the administration a cationic lipid to the subject are provided. The cationic lipids comprise 1,2-dioleoyl-3-trimethylammonium propane (DOTAP), N-1-(2,3-dioleoyloxy)-propyl-N,N,N-trimethyl ammonium chloride (DOTMA), 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (DOEPC), enantiomers and combinations thereof. The compositions may further comprise one or more antigenic components, wherein such components are autologous or nonautologous.

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