Instituto Alberto Luiz Coimbra De Pós Graduação E Pesquisa De Engenharia-COPPE/UFRJ
发明人:
MOITINHO ALVES, Tito Lívio,EISNFELDT, Karen,CAVALCANTE BAPTISTA, Isis,VOLCAN ALMEIDA, Rodrigo,SOBRAL DA COSTA, Elaine,MENKS RIBEIRO, Maria Cecília,POIROT LAND, Marcelo Greradin,LARENTIS, Ariane Leites
申请号：
EP14877857
公开号：
EP3093344A4
申请日:
2014.12.29
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention relates to the construction and optimization of synthetic genes from the Zymomonas mobilis L-asparaginase gene, the method for cloning same and expression thereof in Escherichia coli. The purpose of the production of said enzyme is for producing high levels of a novel L-asparaginase that can be used in L-asparaginase-based pharmaceutical compositions for treating cancer, tumours and diseases involving cell proliferation, as well as for other medical applications.
