A perianal fistula treatment device consists of a coil and a drainage seton. The larger diameter of a tapered portion of the coil is abutted against the tissue surface surrounding the internal opening of the fistula tract. A delivery implement of the delivery mechanism rotates the coil. The implant coil has anti-rewind features 302. The coil closes the fistula internal opening by compressing the tissue surrounding the tract inwardly so that the tissue is brought within close approximation creating a seal impermeable to foreign materials and promoting tissue growth across the closely approximated fistula tract. A drainage seton may have anchoring features provided at a compression zone or region. The seton provides a conduit to drain any abscess and remaining or newly formed exudate and fluids from the fistula tract during the healing process.