A biological thixotropic adhesive that contains dextrin, and at least a structural component that provides thixotropy to the adhesive , and optionally at least an antibiotic that is very useful to stimulate the process of healing of tissues in a patient , for example, to prevent anastomotic leaks of he gastrointestinal system, to affix a prosthesis in inguinal hernioplasties, in a patient and to oclude a fistula in a patient. The biological thixotropic dahesive also has anti-inflammatory properties and can be used with a fatty tissue patch.