The present invention is directed to a device and method, particularly suitable in a temperature adjustment infusion system and more particularly suitable for normothermia and/or hypothermia. The device comprises at least one connection to a reservoir suitable to provide infusion fluid at least one temperature controller adapted to cool and/or heat the temperature of the infusion fluid so that the infusion fluid is delivered with a pre-set temperature at a temperature of between −1° C. and 42° C. at least one flow controller adapted to control the flow downstream the temperature controller in an average amount of between 100 ml and 8000 ml with an average flow rate of preferably 40 ml/h to 8000 ml/h and at least one output adapted to deliver the infusion fluid downstream the reservoir.
