Spacer device, implantable in the human body for the treatment of a bone seat or joint seat or for the two-step treatment of the infections of the joint prostheses, comprising a joint component (2), adapted to be inserted during use in an articular zone of the patient and provided with an external surface (E), a stem component (3), adapted to be implanted during use in a bone or in a residual bone bed of a preceding joint prosthesis, and connection means (4) of adjustable type, wherein at least part of the external surface of the first portion (11) of the stem component (3) and at least part of the external surface (E) of the joint component (2) define a contact surface with the bone tissue and/or adapted for coupling with the bone tissue, wherein the connection means (4) are placed between the joint component (2) and the stem component (3) in order to adjust the distance (G) thereof, wherein the contact surface present in the joint component (2) and/or in the stem component (3) comprises a plurality of recesses (14, 24) for housing a filling material (M) comprising at least one pharmaceutical or medical substance, wherein the plurality of recesses (14, 24) affects or is substantially placed along the entire contact surface or in proximity thereto.
