BENZ, Karin,FREUDIGMANN, Christian,GAISSMAIER, Christoph,HECKY, Jochen,MOLLENHAUER, Jürgen
申请号:
WO2015EP65782
公开号:
WO2016005543(A8)
申请日:
2015.07.10
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要:
The invention relates to a method for in vitro detection of cartilaginous tissue and/or for in vitro determination of the purity of cartilaginous tissue, comprising the following steps: a) treating a tissue sample with a protease and b) testing the protease-treated tissue sample for the presence of protease-resistant fragments of type II collagen and/or type I collagen. The invention further relates to a method for producing a cartilage cell culture, a method for producing an implant charged with cartilage cells, and the use of protease-resistant fragments of type II collagen and/or type I collagen for in vitro detection of cartilaginous tissue and/or for in vitro determination of the purity of cartilaginous tissue, and also the use of a kit for carrying out said methods.