Sangeeta N. Bhatia,Jaideep S. Dudani,Ester J. Kwon,Andrew David Warren
申请号:
US15947644
公开号:
US20180335429A1
申请日:
2018.04.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Aspects of the disclosure relate to methods and compositions useful for in vivo and/or in vitro enzyme profiling. In some embodiments, the disclosure provides methods of in vivo enzymatic processing of exogenous molecules followed by detection of signature molecules as representative of the presence of active enzymes associated with diseases or conditions. In some embodiments, the disclosure provides compositions and in vitro methods for localization of enzymatic activity in a tissue sample.