This invention relates to a kind of anti-oxidation multilayer embedding probiotic particles, which are embedded on the cell wall surface of the cell nucleus by using a plurality of anchoring molecules in the anchoring layer, and then coating the two layers in sequence with a carbohydrate layer and an antioxidant emulsified protein layer to form a complex layer concentric three-dimensional structure. The antioxidant multilayer embedding probiotics granules can effectively improve the anti hygroscopicity deliquescence, storage stability, oxidation resistance, gastric acid tolerance and enzyme decomposition tolerance of probiotics.本創作有關於一種抗氧化多層包埋益生菌顆粒，其係利用錨定層之複數個錨定分子嵌設於菌體核之細胞壁表面，再依序利用醣質層及抗氧化乳化蛋白層包覆二者，以形成複數層同心立體結構。所得的抗氧化多層包埋益生菌顆粒可有效提升益生菌的抗吸濕潮解性、儲存安定性、耐氧化性、胃酸耐受性及酵素分解耐受性。
