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RADIOACTIVE DIAGNOSTIC IMAGING AGENT
专利权人:
NIHON MEDI-PHYSICS CO.; LTD.
发明人:
SHIMADA, TAKAYUKI,NAKATANI, AKIRA,TAKAHASHI, KEIETSU
申请号:
EP06766486
公开号:
EP1894577A4
申请日:
2006.06.08
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
It is intended to provide a radioactive diagnostic imaging agent comprising a radioactive halogen-labeled compound as an active ingredient, in which the active ingredient is prevented from radiolysis and its stability is improved. This is achieved by adding a biologically-acceptable sugar or sugar alcohol to the radioactive diagnostic imaging agent in an amount effective to prevent radiolysis. The amount of the sugar or sugar alcohol to be added is preferably 10 (mmol/L)/GBq/mL or more, and more preferably 50 (mmol/L)/GBq/mL or more. The sugar is preferably selected from the group consisting of erythrose, threose, ribose, arabinose, xylose, lyxose, allose, altrose, glucose, mannose, gulose, idose, galactose, talose, erythrulose, ribulose, xylulose, psicose, fructose, sorbose, and tagatose. The sugar alcohol is preferably selected from the group consisting of erythritol, xylitol, sorbitol, and mannitol.
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