Use of certain quinolone antibiotics to combat Bacterial Diseases of the oral cavity, especially in Veterinary Medicine.Claim 1: a Pharmaceutical composition for the treatment of systemic bacterial infections in the oral cavity, which comprises: a) 8 - cyano - quinolone antibiotics quinolone antibiotics or (b) selected from the group consisting of: garenoxacin, marboflioxacina, Ibafloxacin, danoflox Acina, Difloxacin and orbifloxacina.Claim 2: a composition according to claim 1 which comprises 8 - cyano - quinolone antibiotics of the formula (1) wherein X is H, halogen, alkyl c1-4 alkoxy, c1-4, NH2, and means remains as shown in structures (2) which means C1 alkyl R4 4 caden A linear or branched chain replaced, if necessary, by Hydroxy or methoxy, ciclopropilo,Acyl c1-3, R5 is H, Methyl or phenyl, tienilo piridilo means； R6 H or alkyl c1-4 alkyl or H means； R7 R8 means c1-4, c1-4 alkyl or h； and R1 is a rest ciclopropilo c1-3 alkyl, methoxy -, 2, 4 fl u00faoretilo, - fl u00faorfenilo, 2,4 - difl u00faorfenilo or amino； R2 signifi CA H or alkyl substituted C1 - 6, if necessary, by methoxy or 2-methoxyethoxy and Cyclohexyl,Benzyl 2 - oxopropilo, fenacilo, etoxicarbonilmetilo, pivaloiloximetilo； mean = C (CN)； and their Salts and hydrates pharmaceutically employable. Claim 3 a composition according to claim 1, in which the 8 - cyano - quinolone antibiotic is all.Foreliggende oppfinnelse angår anvendelse av visse quinolon antibiotiske midler for å kontrollere bakterielle sykdommer i det orale hulrommet, særlig innen veterinærmedisin.
