Pharmaceutical composition for the treatment of menopausal syndrome and preparation method thereof, said composition consists of the following weight parts of herbs: Ramulus Cinnamomi 1-3, Rhizoma Zingiberis 0.5-2, Fructus Schisandrae Chinensis 2-4, Flos Inulae 2-4, Herba Lophatheri 3.5-5, Cortex Moutan Radicis 2-4, Fructus Jujubae 0.5-2, Semen Ziziphi Spinosae 2-4, Fructus Corni 2-4, Rehmanniae Recens 2-4, Radix Codonopsis 2-4, and Fructus Gardeniae 0.5-2. All herbs of the composition have synergistic effects to tonify liver and supplement qi, nourish blood and tranquilize mind, clear deficient heat, and relieve restlessness.