SARAF SWARNLATA;SARAF SHAILENDRA;KAUR CHANCHAL DEEP
发明人:
SARAF SWARNLATA,SARAF SWARNLATA,SARAF SHAILENDRA,SARAF SHAILENDRA,KAUR CHANCHAL DEEP,KAUR CHANCHAL DEEP
申请号：
IN2063/DEL/2015
公开号：
IN2015DE02063A
申请日:
2015.07.08
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
Photochemopreventives ameliorate the adverse effects of ultra violet rays on skin and has become an important tool for the fight against photoaging. The effects of photoaging include wrinkles, roughness, dryness, appearance of fine lines and lack of elasticity of skin. Epicatechins are the main antioxidant, anti-carcinogenic polyphenols present in Camellia sinensis (green tea). The aim of this study is to formulate stable creams having herbal novel vesicular systems (liposomes and ethosomes) and study their interaction with skin which was compared in terms of their effects on skin viscoelasticity and skin hydration using cutometer and corneometer respectively. All the formulations improved skin viscoelasticity and skin hydration but novel formulations showed 5-60 fold improved photochemoprevention as compared to conventional formulations. The composition and process for preparing stable green tea extract loaded ethosomal creams will be useful as the better penetration and lipid nature of ethosomes with photoprotective activity of herbs produce the desired effects.
